SCHEMBL14967768

SCHEMBL14967768

CCC1(c2ccc(OC)cc2)OC1C(=O)OC

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.39
ALDH1A1 P00352 3/20 0.39
HPGD P15428 2/20 0.39
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
HSD11B1 P28845 1/20 0.38
HTT P42858 1/20 0.37
POLB P06746 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
GSK3B P49841 1/20 0.36
F2RL1 P55085 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967027 0.89 ALDH1A1 (0.45) SMN1; SMN2ALDH1A1HPGDKDM4ELMNA
SCHEMBL9692237 0.87 TDP1 (0.36) L3MBTL1ALDH1A1HPGDLMNAGAA
SCHEMBL14968329 0.86 HPGD (0.40) ATML3MBTL1SMN1; SMN2ALDH1A1HPGD
SCHEMBL14967899 0.86 CHRM2 (0.37) ATML3MBTL1SMN1; SMN2ALDH1A1HPGD
SCHEMBL14967598 0.86 ELANE (0.36) ATML3MBTL1SMN1; SMN2ALDH1A1HPGD
SCHEMBL9691702 0.85 ALDH1A1 (0.36) ALDH1A1KDM4EHSD11B1
SCHEMBL16110269 0.85 ALDH1A1 (0.40) L3MBTL1SMN1; SMN2ALDH1A1GAAHSD11B1
SCHEMBL14967654 0.85 ATM (0.40) ATML3MBTL1SMN1; SMN2ALDH1A1HPGD
SCHEMBL14967638 0.85 MIF (0.41) L3MBTL1SMN1; SMN2ALDH1A1HPGDKDM4E
SCHEMBL9692301 0.85 HTT (0.45) ATMALDH1A1HTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed