Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439116 | 1.00 | ALDH1A1 (0.40) | ALDH1A1HTTKMT2AMEN1L3MBTL1 | |
| SCHEMBL7442579 | 0.87 | L3MBTL1 (0.37) | ALDH1A1KMT2AMEN1L3MBTL1POLB | |
| SCHEMBL7442583 | 0.87 | L3MBTL1 (0.37) | ALDH1A1KMT2AMEN1L3MBTL1POLB | |
| SCHEMBL14967672 | 0.84 | ALDH1A1 (0.43) | ALDH1A1HTTKMT2AMEN1L3MBTL1 | |
| SCHEMBL21874111 | 0.77 | ALDH1A1 (0.39) | ALDH1A1HTTKMT2AMEN1L3MBTL1 | |
| SCHEMBL21874235 | 0.74 | LMNA (0.46) | ALDH1A1KMT2AMEN1L3MBTL1POLB | |
| SCHEMBL14968165 | 0.73 | CHRM1 (0.44) | ALDH1A1KMT2AMEN1POLBCYP2C9 | |
| SCHEMBL14967816 | 0.72 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1L3MBTL1POLB | |
| SCHEMBL28318807 | 0.72 | OPRM1 (0.57) | LMNASMN1; SMN2NPSR1TDP1CHRM2 | |
| SCHEMBL5166279 | 0.70 | OPRM1 (0.51) | KMT2AMEN1CYP2C9CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869697-A | Process for preparing diltiazem | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 1999-02-09 | — | — | US | claimed |
| US-6180785-B1 | REFLUXING AMINOTHIOPHENOL OR AMINOTHIONAPHTHOL WITH ALKOXYPHENYL-4-CARBOALKOXY-1,3,2-DIOXATHIOLANE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2001-01-30 | — | — | US | disclosed |
| US-5869697-A | Process for preparing diltiazem | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 1999-02-09 | — | — | US | disclosed |