SCHEMBL14968112

SCHEMBL14968112

CCCOC(=O)C1(c2ccccc2)OC1c1ccc(OC)cc1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CHRM5 P08912 1/20 0.41
CHRM1 P11229 1/20 0.41
CHRM3 P20309 1/20 0.41
ALDH1A1 P00352 4/20 0.40
SIGMAR1 Q99720 2/20 0.40
CACNA1D Q01668 1/20 0.39
EDNRA P25101 2/20 0.39
EDNRB P24530 1/20 0.39
LMNA P02545 2/20 0.38
TSHR P16473 1/20 0.38
RECQL P46063 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
KDM4E B2RXH2 1/20 0.38
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
FFAR1 O14842 1/20 0.38
MAOB P27338 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967701 0.95 SIGMAR1 (0.42) CHRM5CHRM1CHRM3ALDH1A1SIGMAR1
SCHEMBL14967936 0.94 ALDH1A1 (0.40) CHRM1ALDH1A1SIGMAR1LMNATSHR
SCHEMBL16109499 0.93 SIGMAR1 (0.41) CHRM5CHRM1CHRM3ALDH1A1SIGMAR1
SCHEMBL16109557 0.92 PPARG (0.42) CHRM5CHRM1CHRM3ALDH1A1SIGMAR1
SCHEMBL14967931 0.90 ALDH1A1 (0.46) ALDH1A1CACNA1DEDNRAEDNRBLMNA
SCHEMBL14967636 0.90 LMNA (0.43) ALDH1A1SIGMAR1LMNATSHRSMN1; SMN2
SCHEMBL16109754 0.89 ALDH1A1 (0.40) CHRM1ALDH1A1LMNATSHRKDM4E
SCHEMBL14967013 0.89 MIF (0.41) CHRM1ALDH1A1SIGMAR1LMNATSHR
SCHEMBL16109264 0.88 LMNA (0.39) ALDH1A1SIGMAR1CACNA1DLMNATSHR
SCHEMBL14967096 0.87 MIF (0.39) CHRM1ALDH1A1SIGMAR1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed