Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9692237 | 0.87 | TDP1 (0.36) | ALDH1A1MAPTOPRM1ITGA4 | |
| SCHEMBL14967768 | 0.85 | ATM (0.44) | ALDH1A1HSD11B1KDM4E | |
| SCHEMBL9692301 | 0.85 | HTT (0.45) | ALDH1A1SLC6A4HCAR3HCAR2MAPT | |
| SCHEMBL9692273 | 0.77 | SLC6A3 (0.37) | ALDH1A1SLC6A3SLC6A4HCAR3HCAR2 | |
| SCHEMBL16109613 | 0.75 | LMNA (0.39) | ALDH1A1MAPTOPRM1TSHR | |
| SCHEMBL14967027 | 0.74 | ALDH1A1 (0.45) | ALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL14967654 | 0.74 | ATM (0.40) | ALDH1A1SLC6A3SLC6A4HSD11B1KDM4E | |
| SCHEMBL9692311 | 0.73 | SLC6A3 (0.37) | SLC6A3SLC6A4HCAR3HCAR2RORC | |
| SCHEMBL16109685 | 0.73 | SCN1A (0.36) | ALDH1A1SLC6A3SLC6A4HSD11B1OPRM1 | |
| SCHEMBL9692027 | 0.73 | DNTT (0.35) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153692-B1 | METHOD FOR ISOMERIZATION A GLYCIDATE DERIVATIVE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-4621150-A | METAL PERHALATE OR SULFONATE OR COMPLEX; GLYCIDATE, 2-HYDROXY-3-BUTENOATE, EPOXIDE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-11-04 | — | — | US | disclosed |
| EP-0153692-A2 | Method for isomerization a glycidate derivative | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1985-09-04 | — | — | EP | disclosed |