SCHEMBL14967880

SCHEMBL14967880

CCOC(=O)C1(c2ccc(OC)cc2)OC12CCC2

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.46
LMNA P02545 2/20 0.46
NPSR1 Q6W5P4 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
POLB P06746 4/20 0.44
CYP2C19 P33261 2/20 0.44
CYP2C9 P11712 1/20 0.44
ALDH1A1 P00352 8/20 0.42
KMT2A Q03164 3/20 0.42
CHRM2 P08172 1/20 0.41
CHRM1 P11229 1/20 0.41
P2RX7 Q99572 2/20 0.40
MEN1 O00255 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
GAA P10253 1/20 0.39
CYP3A4 P08684 1/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967669 0.97 LMNA (0.49) SMN1; SMN2LMNANPSR1TDP1POLB
SCHEMBL14967662 0.96 LMNA (0.48) SMN1; SMN2LMNANPSR1TDP1POLB
SCHEMBL14967955 0.90 CHRM1 (0.45) SMN1; SMN2LMNANPSR1TDP1POLB
SCHEMBL14967442 0.89 CHRM1 (0.44) SMN1; SMN2LMNANPSR1TDP1POLB
SCHEMBL14967200 0.88 OPRM1 (0.49) SMN1; SMN2LMNATDP1ALDH1A1KMT2A
SCHEMBL14967849 0.87 CHRM1 (0.47) SMN1; SMN2LMNANPSR1TDP1POLB
SCHEMBL14967071 0.87 CHRM1 (0.43) SMN1; SMN2LMNANPSR1TDP1POLB
SCHEMBL14968066 0.86 ALDH1A1 (0.43) SMN1; SMN2LMNANPSR1TDP1POLB
SCHEMBL14968164 0.86 CHRM2 (0.47) SMN1; SMN2LMNANPSR1TDP1POLB
SCHEMBL14966959 0.86 CHRM1 (0.47) SMN1; SMN2LMNANPSR1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed