SCHEMBL14968183

SCHEMBL14968183

COC(=O)C1(c2ccccc2)OC12CCC2

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
HTT P42858 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.39
AKR1C1 Q04828 1/20 0.39
ALDH1A1 P00352 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HDAC4 P56524 2/20 0.38
CHRM3 P20309 1/20 0.37
NR1H2 P55055 2/20 0.37
NR1H3 Q13133 2/20 0.37
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
HSD11B1 P28845 1/20 0.36
APOBEC3A P31941 1/20 0.36
APOBEC3G Q9HC16 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14968268 0.97 MEN1 (0.46) MEN1KMT2AHTTL3MBTL1AKR1C1
SCHEMBL14967505 0.95 MEN1 (0.45) MEN1KMT2AHTTL3MBTL1AKR1C1
SCHEMBL14967244 0.86 CYP3A4 (0.42) ALDH1A1SMN1; SMN2CYP3A4
SCHEMBL14968066 0.85 ALDH1A1 (0.43) KMT2AL3MBTL1ALDH1A1SMN1; SMN2CYP3A4
SCHEMBL14967282 0.84 APOBEC3A (0.42) MEN1KMT2AHTTAKR1C1ALDH1A1
SCHEMBL14968122 0.84 SMN1; SMN2 (0.55) MEN1KMT2ASMN1; SMN2CYP3A4
SCHEMBL14967774 0.84 SMN1; SMN2 (0.36) MEN1KMT2AAKR1C1ALDH1A1SMN1; SMN2
SCHEMBL14967884 0.84 CHRM3 (0.46) MEN1KMT2AHTTAKR1C1ALDH1A1
SCHEMBL14968235 0.83 POLB (0.42) L3MBTL1AKR1C1ALDH1A1SMN1; SMN2HDAC4
SCHEMBL14968327 0.83 CYP3A4 (0.42) ALDH1A1SMN1; SMN2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed