SCHEMBL14967282

SCHEMBL14967282

CC(C)OC(=O)C1(c2ccccc2)OC12CCC2

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
APOBEC3A P31941 2/20 0.42
APOBEC3G Q9HC16 2/20 0.42
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.36
SMN1; SMN2 Q16637 4/20 0.36
AKR1C1 Q04828 1/20 0.36
PDCD1 Q15116 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
LMNA P02545 3/20 0.35
NPC1 O15118 1/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35
HPGD P15428 1/20 0.35
MAPK1 P28482 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967459 0.97 APOBEC3A (0.45) APOBEC3AAPOBEC3GALDH1A1TSHRSMN1; SMN2
SCHEMBL14967392 0.96 APOBEC3A (0.44) APOBEC3AAPOBEC3GALDH1A1TSHRSMN1; SMN2
SCHEMBL14967801 0.89 ABHD10 (0.37) ALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL14968196 0.86 ABHD10 (0.37) APOBEC3AAPOBEC3GALDH1A1SMN1; SMN2LMNA
SCHEMBL14967675 0.85 HPGD (0.43) ALDH1A1SMN1; SMN2LMNANPC1RAB9A
SCHEMBL14968058 0.84 ABHD10 (0.36) APOBEC3AAPOBEC3GALDH1A1SMN1; SMN2LMNA
SCHEMBL14968183 0.84 MEN1 (0.46) APOBEC3AAPOBEC3GALDH1A1TSHRSMN1; SMN2
SCHEMBL14967783 0.82 SLC6A4 (0.46) ALDH1A1SMN1; SMN2LMNANPC1RAB9A
SCHEMBL14967683 0.81 SLC6A4 (0.48) ALDH1A1SMN1; SMN2LMNANPC1RAB9A
SCHEMBL14968268 0.81 MEN1 (0.46) APOBEC3AAPOBEC3GALDH1A1TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed