SCHEMBL14967459

SCHEMBL14967459

CC(C)OC(=O)C1(c2ccccc2)OC12CCCC2

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
APOBEC3A P31941 2/20 0.45
APOBEC3G Q9HC16 2/20 0.45
AKR1C1 Q04828 1/20 0.39
ALDH1A1 P00352 3/20 0.39
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
TSHR P16473 1/20 0.36
PRCP P42785 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
HDAC4 P56524 2/20 0.36
PDCD1 Q15116 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
POLB P06746 1/20 0.35
CHRM3 P20309 1/20 0.35
NPC1 O15118 1/20 0.35
LMNA P02545 1/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967392 0.99 APOBEC3A (0.44) APOBEC3AAPOBEC3GAKR1C1ALDH1A1MAPK1
SCHEMBL14967282 0.97 APOBEC3A (0.42) APOBEC3AAPOBEC3GAKR1C1ALDH1A1MAPK1
SCHEMBL14968196 0.89 ABHD10 (0.37) APOBEC3AAPOBEC3GALDH1A1SMN1; SMN2POLB
SCHEMBL14968058 0.87 ABHD10 (0.36) APOBEC3AAPOBEC3GALDH1A1SMN1; SMN2POLB
SCHEMBL14967801 0.86 ABHD10 (0.37) ALDH1A1SMN1; SMN2POLBLMNA
SCHEMBL14967783 0.85 SLC6A4 (0.46) ALDH1A1MAPK1SMN1; SMN2POLBNPC1
SCHEMBL14967683 0.84 SLC6A4 (0.48) ALDH1A1MAPK1SMN1; SMN2POLBNPC1
SCHEMBL14968268 0.84 MEN1 (0.46) APOBEC3AAPOBEC3GAKR1C1ALDH1A1SMN1; SMN2
SCHEMBL14967505 0.82 MEN1 (0.45) APOBEC3AAPOBEC3GAKR1C1ALDH1A1TSHR
SCHEMBL14967675 0.82 HPGD (0.43) ALDH1A1MAPK1SMN1; SMN2POLBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed