SCHEMBL1496943

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1482326	0.95	AVPR1A (0.41)	KCNH2CYP1A2CYP2C18CYP2C19HDAC3
	SCHEMBL4224059	0.89	HDAC1 (0.43)	KCNH2HDAC3HDAC2MCHR1HDAC1
	SCHEMBL1496929	0.88	ALDH1A1 (0.39)	KCNH2CYP1A2CYP2C18CYP2C19HDAC3
	SCHEMBL1496902	0.88	AVPR1A (0.39)	KCNH2CYP1A2CYP2C18CYP2C19HDAC3
	SCHEMBL1497121	0.88	KDM4E (0.40)	KCNH2CYP1A2CYP2C18CYP2C19HDAC3
	SCHEMBL1497036	0.87	USP2 (0.45)	HRH3ALDH1A1GAAMEN1KMT2A
	SCHEMBL1496879	0.86	CSF1R (0.36)	CYP1A2CYP2C19MCHR1PDCD1CD274
	SCHEMBL1497079	0.86	USP2 (0.42)	HRH3ALDH1A1GAAMEN1KMT2A
	SCHEMBL1482611	0.85	PDCD1 (0.38)	HDAC3HDAC2PDCD1CD274HDAC1
	SCHEMBL7999005	0.85	HDAC3 (0.39)	KCNH2CYP1A2CYP2C18CYP2C19HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.