SCHEMBL14969560

SCHEMBL14969560

CC(Cc1cccc(Nc2ccc(NCc3cc(C(C)(C)C)c(O)c(C(C)(C)C)c3)cc2)c1)CC(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GSR P00390 2/20 0.39
SCN2A Q99250 2/20 0.39
HIF1A Q16665 5/20 0.35
FFAR1 O14842 2/20 0.35
MEN1 O00255 1/20 0.34
GAA P10253 1/20 0.34
KMT2A Q03164 1/20 0.34
HMGCR P04035 1/20 0.33
EGFR P00533 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12890012 0.90 GSR (0.40) GSRSCN2AHIF1AFFAR1MEN1
SCHEMBL2788436 0.90 GSR (0.40) GSRSCN2AHIF1AFFAR1MEN1
SCHEMBL2807290 0.90 GSR (0.40) GSRSCN2AHIF1AFFAR1MEN1
SCHEMBL14534672 0.87 FFAR1 (0.33) HIF1AFFAR1
SCHEMBL2788958 0.84 SCN2A (0.35) GSRSCN2AFFAR1MEN1GAA
SCHEMBL14534436 0.82 GSR (0.36) GSRSCN2AHIF1AFFAR1MEN1
SCHEMBL12377559 0.81 MEN1 (0.47) GSRSCN2AHIF1AMEN1GAA
SCHEMBL9912714 0.81 EGFR (0.32) GSRFFAR1EGFR
SCHEMBL784945 0.80 GAA (0.50) GSRSCN2AHIF1AMEN1GAA
SCHEMBL14493851 0.80 GAA (0.50) GSRSCN2AHIF1AMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9523060-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2016-12-20 US disclosed
US-9388120-B2 Nitrogen and hindered phenol containing dual functional macromolecular antioxidants: synthesis, performances and applications POLNOX CORPORATION (US) 2016-07-12 US disclosed
US-20150159109-A1 Lubricant Oil Compositions POLNOX CORPORATION 2015-06-11 US disclosed
US-8927472-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2015-01-06 US disclosed
US-20140316163-A1 NITROGEN AND HINDERED PHENOL CONTAINING DUAL FUNCTIONAL MACROMOLECULAR ANTIOXIDANTS: SYNTHESIS, PERFORMANCES AND APPLICATIONS POLNOX CORPORATION (US) 2014-10-23 US disclosed
US-20130130955-A1 LUBRICANT OIL COMPOSITIONS POLNOX CORPORATION (US) 2013-05-23 US disclosed
US-8080689-B2 Nitrogen and hindered phenol containing dual functional macromolecular antioxidants: synthesis, performances and applications POLNOX CORPORATION (US) 2011-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140316163-A1 NITROGEN AND HINDERED PHENOL CONTAINING DUAL FUNCTIONAL MACROMOLECULAR ANTIOXIDANTS: SYNTHESIS, PERFORMANCES AND APPLICATIONS CAT, LPO, DUOX1 GSR 54/4885SCN2A 3644/4885HIF1A 505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.