SCHEMBL1496967

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1497071	0.93	ROCK2 (0.39)	HTR5AHDAC1ROCK1ROCK2PDCD1
	SCHEMBL1497106	0.93	ROCK1 (0.38)	HDAC1ROCK1ROCK2PDCD1CD274
	SCHEMBL1496972	0.92	NAMPT (0.42)	HDAC1ROCK1ALDH1A1HPGDROCK2
	SCHEMBL1496862	0.92	HTR5A (0.40)	HTR5AHDAC1ROCK1ROCK2CKS1B
	SCHEMBL1497000	0.92	CYP3A4 (0.39)	HDAC1ROCK1KDM4EALDH1A1HPGD
	SCHEMBL1496854	0.91	HTR5A (0.37)	HTR5AHDAC1ROCK1ALDH1A1HPGD
	SCHEMBL1496875	0.91	HTR5A (0.39)	HTR5AHDAC1ROCK1ROCK2CKS1B
	SCHEMBL1497029	0.91	ROCK2 (0.42)	HDAC1ROCK1ROCK2PDCD1CD274
	SCHEMBL1496904	0.90	ROCK2 (0.44)	ROCK1KDM4EALDH1A1HPGDHSD17B10
	SCHEMBL1496961	0.90	PDCD1 (0.36)	HDAC1ROCK1ROCK2CKS1BSKP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.