Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | TACR2 | P21452 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1497137 | 0.96 | HDAC3 (0.39) | HDAC3HDAC2DYRK1AKMT2AKDM4E | |
| SCHEMBL4229607 | 0.92 | HDAC1 (0.43) | HDAC3HDAC2DYRK1AKMT2AKDM4E | |
| SCHEMBL1497209 | 0.92 | ALDH1A1 (0.41) | KMT2AKDM4EHSD17B10HIF1ATACR2 | |
| SCHEMBL1482240 | 0.91 | ALDH1A1 (0.40) | KMT2AKDM4EHSD17B10HIF1ATACR2 | |
| SCHEMBL1497039 | 0.90 | CYP1A2 (0.37) | HDAC3HDAC2DYRK1AKMT2AKDM4E | |
| SCHEMBL1496947 | 0.89 | SIGMAR1 (0.41) | DYRK1AKMT2ACACNA1FADORA3DRD2 | |
| SCHEMBL1497050 | 0.88 | ALDH1A1 (0.40) | KDM4EHIF1ATACR2EPHX2ALDH1A1 | |
| SCHEMBL1497166 | 0.88 | ALDH1A1 (0.41) | HDAC3HDAC2KMT2AKDM4EHSD17B10 | |
| SCHEMBL4223072 | 0.88 | HDAC1 (0.44) | HDAC3HDAC2DYRK1AKMT2AHDAC1 | |
| SCHEMBL1497005 | 0.86 | UTS2R (0.42) | HDAC3HDAC2KMT2AHDAC1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292611-A1 | NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2011-03-09 | — | — | EP | disclosed |