Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 9/20 | 0.54 |
| ▸ | HTR1A | P08908 | 8/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 5/20 | 0.51 |
| ▸ | HTR6 | P50406 | 4/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14970552 | 0.85 | HTT (0.64) | HTTKDM4EL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL14970587 | 0.79 | L3MBTL1 (0.90) | HTTKDM4EL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL14970718 | 0.79 | L3MBTL1 (0.90) | HTTKDM4EL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL23366615 | 0.77 | KDM4E (0.61) | KDM4EALDH1A1SMN1; SMN2KMT2ATDP1 | |
| SCHEMBL15331415 | 0.76 | KDM4E (0.63) | KDM4EALDH1A1SMN1; SMN2KMT2ATDP1 | |
| SCHEMBL14970717 | 0.76 | KDM4E (0.88) | HTTKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL22500372 | 0.74 | L3MBTL1 (0.60) | HTTKDM4EL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL17848618 | 0.74 | HTR1A (0.61) | KDM4EALDH1A1SMN1; SMN2KMT2ATDP1 | |
| SCHEMBL14084433 | 0.74 | L3MBTL1 (0.73) | HTTKDM4EL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5388793 | 0.73 | HRH3 (0.71) | KDM4EALDH1A1SMN1; SMN2TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074965-A1 | AMINOALKYL PHENOL ETHER INHIBITORS OF INFLUENZA A VIRUS | MICROBIOTIX, INC. (US) | 2013-05-23 | — | — | WO | disclosed |