Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14970451 | 0.85 | HTT (0.66) | HTTKDM4EL3MBTL1HRH3ALDH1A1 | |
| SCHEMBL19216371 | 0.80 | TDP1 (0.69) | KDM4EHRH3ALDH1A1LMNAMEN1 | |
| SCHEMBL17848522 | 0.79 | HRH3 (0.59) | KDM4EHRH3ALDH1A1LMNAMEN1 | |
| SCHEMBL17848423 | 0.79 | TSHR (0.66) | KDM4EL3MBTL1HRH3ALDH1A1LMNA | |
| SCHEMBL14970718 | 0.78 | L3MBTL1 (0.90) | HTTKDM4EL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL14970587 | 0.78 | L3MBTL1 (0.90) | HTTKDM4EL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL19389876 | 0.76 | KDM4E (0.75) | KDM4EHRH3ALDH1A1LMNA | |
| SCHEMBL11173592 | 0.75 | KDM4E (0.61) | KDM4EHRH3ALDH1A1LMNAMEN1 | |
| SCHEMBL7221127 | 0.73 | HRH3 (0.57) | KDM4EHRH3ALDH1A1LMNAMEN1 | |
| SCHEMBL14084433 | 0.73 | L3MBTL1 (0.73) | HTTKDM4EL3MBTL1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074965-A1 | AMINOALKYL PHENOL ETHER INHIBITORS OF INFLUENZA A VIRUS | MICROBIOTIX, INC. (US) | 2013-05-23 | — | — | WO | disclosed |