Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TACR2 | P21452 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1497209 | 0.96 | ALDH1A1 (0.41) | ALDH1A1GAAL3MBTL1POLBTACR2 | |
| SCHEMBL1482240 | 0.95 | ALDH1A1 (0.40) | ALDH1A1GAAL3MBTL1POLBTACR2 | |
| SCHEMBL1497166 | 0.93 | ALDH1A1 (0.41) | ALDH1A1GAAL3MBTL1POLBTACR2 | |
| SCHEMBL2383602 | 0.89 | MAPT (0.43) | ALDH1A1GAAL3MBTL1POLBTACR2 | |
| SCHEMBL1497011 | 0.88 | SIGMAR1 (0.41) | ALDH1A1GAATACR2LMNAMAPT | |
| SCHEMBL1496898 | 0.88 | HDAC3 (0.38) | ALDH1A1TACR2HIF1AEPHX2KDM4E | |
| SCHEMBL1482270 | 0.87 | SMN1; SMN2 (0.36) | ALDH1A1GAAL3MBTL1HTTLMNA | |
| SCHEMBL4234597 | 0.87 | MAPT (0.43) | ALDH1A1GAAL3MBTL1POLBTACR2 | |
| SCHEMBL1497026 | 0.87 | POLB (0.45) | ALDH1A1GAAL3MBTL1POLBTACR2 | |
| SCHEMBL4229423 | 0.86 | MAPT (0.42) | ALDH1A1GAAL3MBTL1POLBTACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292611-B1 | NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE | SANTEN PHARMACEUTICAL CO LTD (JP) | 2012-07-25 | — | — | EP | disclosed |
| EP-2292611-A1 | NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2011-03-09 | — | — | EP | disclosed |