Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.88 |
| ▸ | PSMB1 | P20618 | 5/20 | 0.72 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.72 |
| ▸ | PSMB2 | P49721 | 4/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.60 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.60 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14966268 | 0.98 | LTA4H (0.86) | LTA4HPSMB1PSMB5PSMB2KDM4E | |
| Boxidine SCHEMBL633445 | 0.94 | LTA4H (0.83) | LTA4HPSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL4174980 | 0.86 | LTA4H (0.71) | LTA4HPSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL24529993 | 0.84 | LTA4H (0.69) | LTA4HPSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL17694433 | 0.84 | KDM4E (0.97) | LTA4HPSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL12780029 | 0.84 | KDM4E (0.97) | LTA4HPSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL7139384 | 0.83 | LTA4H (1.00) | LTA4HPSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL12439972 | 0.83 | LTA4H (0.67) | LTA4HPSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL19716249 | 0.82 | PSMB1 (0.97) | LTA4HPSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL270794 | 0.82 | KDM4E (1.00) | LTA4HPSMB1PSMB5PSMB2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074965-A1 | AMINOALKYL PHENOL ETHER INHIBITORS OF INFLUENZA A VIRUS | MICROBIOTIX, INC. (US) | 2013-05-23 | — | — | WO | disclosed |