Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.69 |
| ▸ | DRD2 | P14416 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.52 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HRH2 | P25021 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7247185 | 0.93 | HRH3 (0.60) | LTA4HDRD2ALDH1A1MAPTMEN1 | |
| SCHEMBL31705697 | 0.90 | LTA4H (0.57) | LTA4HDRD2ALDH1A1MAPTMEN1 | |
| SCHEMBL13761571 | 0.85 | KDM4E (0.75) | LTA4HKDM4EPSMB1PSMB5PSMB2 | |
| SCHEMBL14970712 | 0.84 | LTA4H (0.88) | LTA4HKDM4EPSMB1PSMB5PSMB2 | |
| Hydrochloric Acid SCHEMBL14966268 | 0.83 | LTA4H (0.86) | LTA4HKDM4EPSMB1PSMB5PSMB2 | |
| SCHEMBL4174980 | 0.83 | LTA4H (0.71) | LTA4HDRD2KDM4EL3MBTL1PSMB1 | |
| SCHEMBL1730763 | 0.83 | LTA4H (0.67) | LTA4HDRD2KDM4EALDH1A1MAPT | |
| Boxidine SCHEMBL633445 | 0.82 | LTA4H (0.83) | LTA4HDRD2KDM4EPSMB1PSMB5 | |
| SCHEMBL13930954 | 0.81 | KDM4E (0.57) | LTA4HKDM4EPSMB1PSMB5PSMB2 | |
| SCHEMBL13952428 | 0.81 | HRH3 (0.67) | KDM4EHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022130352-A1 | NOVEL COMPOUNDS SUITABLE FOR THE TREATMENT OF DYSLIPIDEMIA | CADILA HEALTHCARE LIMITED (IN) | 2022-06-23 | — | — | WO | disclosed |