SCHEMBL1497086

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29793217	1.00	KIF11 (0.60)	KIF11CA1CA2CA9CA12
	SCHEMBL7082554	0.84	KIF11 (0.59)	KIF11CA1CA2CA9CA12
	SCHEMBL15867028	0.84	VCAM1 (0.48)	KIF11ERAP1SLC22A12
	SCHEMBL23633376	0.83	CA2 (0.52)	KIF11CA1CA2CA9CA12
	SCHEMBL1541448	0.81	KIF11 (0.51)	KIF11CA1CA2CA9CA12
	SCHEMBL29913597	0.81	KIF11 (0.51)	KIF11CA1CA2CA9CA12
	SCHEMBL29780618	0.81	CA2 (0.55)	KIF11CA1CA2CA9CA12
	SCHEMBL11685070	0.81	CA12 (0.58)	KIF11CA1CA2CA9CA12
	SCHEMBL585873	0.81	KIF11 (0.60)	KIF11PTGS1PTGS2ERAP1SLC22A12
	SCHEMBL67150	0.81	CCR2 (0.45)	KIF11ERAP1SLC22A12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.