Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.55 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.51 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103228 | 0.81 | SMN1; SMN2 (0.63) | PARP10CA1CA2PRSS1PRSS2 | |
| SCHEMBL103227 | 0.81 | SMN1; SMN2 (0.63) | PARP10CA1CA2PRSS1PRSS2 | |
| SCHEMBL9892335 | 0.79 | PRSS1 (0.61) | PARP10CA1CA2PRSS1PRSS2 | |
| SCHEMBL5423613 | 0.78 | NOS3 (0.68) | PARP10CA1CA2PRSS1PRSS2 | |
| SCHEMBL22044399 | 0.76 | NOS3 (0.55) | PARP10CA1CA2PRSS1PRSS2 | |
| SCHEMBL6913760 | 0.76 | CA1 (0.52) | PARP10CA1CA2PRSS1PRSS2 | |
| SCHEMBL3052606 | 0.76 | LMNA (0.65) | PARP10CA1CA2PRSS1PRSS2 | |
| SCHEMBL3052608 | 0.76 | LMNA (0.65) | PARP10CA1CA2PRSS1PRSS2 | |
| SCHEMBL10925317 | 0.75 | CA1 (0.67) | PARP10CA1CA2PRSS1PRSS2 | |
| SCHEMBL17547216 | 0.75 | PARP10 (0.50) | PARP10CA1CA2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074059-A2 | CYTOSINE DEAMINASE MODULATORS FOR ENHANCEMENT OF DNA TRANSFECTION | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2013-05-23 | — | — | WO | disclosed |