SCHEMBL103228

SCHEMBL103228

COc1ccc(C(N)=NO)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.63
ALDH1A1 P00352 1/20 0.63
RAB9A P51151 5/20 0.59
GAA P10253 4/20 0.59
PARP10 Q53GL7 2/20 0.57
PRSS1 P07477 1/20 0.57
PRSS2 P07478 1/20 0.57
PRSS3 P35030 1/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
PARP1 P09874 1/20 0.57
PARP2 Q9UGN5 1/20 0.57
PARP4 Q9UKK3 1/20 0.57
LMNA P02545 2/20 0.56
KMT2A Q03164 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
GFER P55789 1/20 0.56
RECQL P46063 1/20 0.55
NPC1 O15118 4/20 0.54
MAPT P10636 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL103227 1.00 SMN1; SMN2 (0.63) SMN1; SMN2ALDH1A1RAB9AGAAPARP10
SCHEMBL3052606 0.94 LMNA (0.65) SMN1; SMN2ALDH1A1RAB9AGAAPARP10
SCHEMBL3052608 0.94 LMNA (0.65) SMN1; SMN2ALDH1A1RAB9AGAAPARP10
SCHEMBL18796192 0.89 PTGIR (0.65) SMN1; SMN2ALDH1A1RAB9AGAAPARP10
SCHEMBL23864974 0.83 KDM4E (0.56) SMN1; SMN2ALDH1A1RAB9AGAAPARP10
SCHEMBL14970879 0.81 PARP10 (0.55) SMN1; SMN2ALDH1A1RAB9AGAAPARP10
SCHEMBL9892335 0.81 PRSS1 (0.61) SMN1; SMN2ALDH1A1RAB9AGAAPARP10
SCHEMBL21215222 0.81 KDM1A (0.60) ALDH1A1RAB9AGAALMNAKMT2A
SCHEMBL18615326 0.80 GAA (0.56) SMN1; SMN2ALDH1A1RAB9AGAAPARP10
SCHEMBL5423613 0.79 NOS3 (0.68) SMN1; SMN2ALDH1A1RAB9AGAAPARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12180172-B1 [3-(4-Methoxyphenyl)-1,2,4-oxadiazol-5-yl]methanol as an antitumor and antimicrobial compound King Faisal University (SA) 2024-12-31 US claimed
US-11981647-B1 3-(4-methoxyphenyl)-5-{[5-methyl-2-(propan-2-yl)phenoxy]methyl}-1,2,4-oxadiazole as an antitumor and antimicrobial compound King Faisal University (SA) 2024-05-14 US claimed
US-11897850-B1 N′-(2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetoxy)-4-methoxybenzimidamide as an antimicrobial compound King Faisal University (SA) 2024-02-13 US claimed
US-11891366-B1 4-methoxy-n′-(2-(5-phenyl-1,3,4-oxadiazol-2-ylthio)acetoxy)benzimidamide as an antimicrobial compound King Faisal University (SA) 2024-02-06 US claimed
WO-2025224512-A1 NOVEL COMPOUND AS 17-BETA-HYDROXYSTEROID DEHYDROGENASE 13 (HSD17B13) INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 삼진제약주식회사 2025-10-30 WO disclosed
US-12448372-B2 Class of triaromatic compounds targeting bifunctional phosphorylation site of STAT3 and applications thereof Shanghai Yuyao Biotech Ltd. (CN) 2025-10-21 US disclosed
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 US disclosed
EP-3634403-B1 PHENYL-HETEROCYCLE-PHENYL DERIVATIVES FOR USE IN THE TREATMENT OR PREVENTION OF MELANOMA MAX PLANCK GESELLSCHAFT (DE) 2025-06-25 EP disclosed
US-12275723-B2 Compounds and uses thereof JANSSEN PHARMACEUTICA NV (BE) 2025-04-15 US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 US disclosed
US-20250091999-A1 [3-(4-METHOXYPHENYL)-1,2,4-OXADIAZOL-5-YL]METHANOL AS AN ANTITUMOR AND ANTIMICROBIAL COMPOUND UNIV KING FAISAL (SA) 2025-03-20 US disclosed
WO-1995016686-A1 HETEROARYL MUPIROCIN DERIVATIVES USEFUL AS ANTIBACTERIAL, ANTIFUNGAL OR HERBICIDAL AGENTS SMITHKLINE BEECHAM PLC (GB) 1995-06-22 WO disclosed
US-5364865-A Phenoxy- and phenoxyalkyl-piperidines as antiviral agents STERLING WINTHROP INC. (US) 1994-11-15 US disclosed
EP-0605031-A1 Phenoxy- and phenoxyalkyl-piperidines as antiviral agents STERLING WINTHROP INC. (US) 1994-07-06 EP disclosed
US-4853383-A β-blocking substituted imidazoles MERCK & CO., INC. (US) 1989-08-01 US disclosed
US-4642311-A β-adrenergic blocking imidazolylphenoxy propanolamines MERCK & CO., INC. (US) 1987-02-10 US disclosed
US-4142044-A FLUORESCENT DYES HOECHST AKTIENGESELLSCHAFT (DE) 1979-02-27 US disclosed
US-4016170-A TRANQUILIZERS, SLEEP INDUCERS SANDOZ, INC. (US) 1977-04-05 US disclosed
US-3994907-A Coumarin derivatives, their preparation and their use as optical brightening agents PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11891366-B1 4-methoxy-n′-(2-(5-phenyl-1,3,4-oxadiazol-2-ylthio)acetoxy)benzimidamide as an antimicrobial compound IL4I1, AADAC, CASP4 SMN1; SMN2 2240/4885ALDH1A1 1134/4885RAB9A 3868/4885
US-20250091999-A1 [3-(4-METHOXYPHENYL)-1,2,4-OXADIAZOL-5-YL]METHANOL AS AN ANTITUMOR AND ANTIMICROBIAL COMPOUND OXA1L, MCL1, CASP3 SMN1; SMN2 2851/4885ALDH1A1 764/4885RAB9A 2683/4885
US-12275723-B2 Compounds and uses thereof NLN, ACHE, CLN6 SMN1; SMN2 13/4885ALDH1A1 656/4885RAB9A 2129/4885
US-11897850-B1 N′-(2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetoxy)-4-methoxybenzimidamide as an antimicrobial compound B3GNT2, IL4I1, NIT2 SMN1; SMN2 3257/4885ALDH1A1 1271/4885RAB9A 3509/4885
US-12448372-B2 Class of triaromatic compounds targeting bifunctional phosphorylation site of STAT3 and applications thereof STAT3, JAK2, STAT1 SMN1; SMN2 4748/4885ALDH1A1 1654/4885RAB9A 3604/4885
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 SMN1; SMN2 3115/4885ALDH1A1 4471/4885RAB9A 2370/4885
US-12180172-B1 [3-(4-Methoxyphenyl)-1,2,4-oxadiazol-5-yl]methanol as an antitumor and antimicrobial compound OXA1L, MCL1, CASP3 SMN1; SMN2 2851/4885ALDH1A1 764/4885RAB9A 2683/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 SMN1; SMN2 3115/4885ALDH1A1 4471/4885RAB9A 2370/4885
US-11981647-B1 3-(4-methoxyphenyl)-5-{[5-methyl-2-(propan-2-yl)phenoxy]methyl}-1,2,4-oxadiazole as an antitumor and antimicrobial compound OXA1L, API5, MCL1 SMN1; SMN2 3510/4885ALDH1A1 1734/4885RAB9A 3147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.