Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PTPRF | P10586 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPRA | P18433 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965773 | 0.93 | L3MBTL1 (0.46) | ALDH1A1LMNAMAPTKCNJ1SMN1; SMN2 | |
| SCHEMBL14971091 | 0.91 | DRD2 (0.44) | ALDH1A1LMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL14965513 | 0.91 | LSS (0.46) | ALDH1A1TSHRLMNAMAPTKCNJ1 | |
| SCHEMBL14965550 | 0.90 | SLC2A1 (0.39) | ALDH1A1TSHRLMNAMAPTKCNJ1 | |
| SCHEMBL14965368 | 0.90 | KCNJ1 (0.40) | ALDH1A1LMNAMAPTKCNJ1SMN1; SMN2 | |
| SCHEMBL14965746 | 0.89 | DRD2 (0.41) | ALDH1A1LMNAMAPTKCNJ1SMN1; SMN2 | |
| SCHEMBL14965775 | 0.89 | L3MBTL1 (0.41) | ALDH1A1LMNAMAPTKCNJ1SMN1; SMN2 | |
| SCHEMBL14965511 | 0.89 | LTA4H (0.40) | ALDH1A1LMNAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL14965626 | 0.89 | LTA4H (0.40) | ALDH1A1LMNAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL14966198 | 0.89 | KCNJ1 (0.40) | ALDH1A1LMNAMAPTKCNJ1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |