Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14971108 | 0.89 | ALDH1A1 (0.44) | L3MBTL1GAARAB9AALDH1A1MAPT | |
| SCHEMBL14965773 | 0.87 | L3MBTL1 (0.46) | L3MBTL1GAARAB9AALDH1A1KMT2A | |
| SCHEMBL14965823 | 0.85 | CLK2 (0.39) | L3MBTL1ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL14965513 | 0.84 | LSS (0.46) | ALDH1A1MAPTSMN1; SMN2POLBLMNA | |
| SCHEMBL14965682 | 0.83 | HTR7 (0.44) | ALDH1A1KMT2AMEN1KDM4EPOLB | |
| SCHEMBL14965907 | 0.83 | TBK1 (0.37) | L3MBTL1ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL14965488 | 0.83 | ALDH1A1 (0.40) | L3MBTL1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL14965999 | 0.83 | ALDH1A1 (0.43) | ALDH1A1MAPTSMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL14966198 | 0.82 | KCNJ1 (0.40) | ALDH1A1MAPTSMN1; SMN2POLBLMNA | |
| SCHEMBL14965550 | 0.82 | SLC2A1 (0.39) | ALDH1A1MAPTSMN1; SMN2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | claimed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |