Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 10/20 | 0.44 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | CBFB | Q13951 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15231839 | 0.79 | NPBWR1 (0.43) | NPBWR1DGAT1KCNH2CBFBSOAT1 | |
| SCHEMBL19137954 | 0.77 | DGAT1 (0.47) | NPBWR1AGPAT2DGAT1KCNH2CBFB | |
| SCHEMBL15245205 | 0.76 | NPBWR1 (0.53) | NPBWR1DGAT1KCNH2SOAT1 | |
| SCHEMBL24075258 | 0.76 | NPBWR1 (0.56) | NPBWR1DGAT1KCNH2SOAT1ALDH1A1 | |
| SCHEMBL666767 | 0.74 | NPBWR1 (0.43) | NPBWR1DGAT1KCNH2CBFBKDM4E | |
| SCHEMBL2360765 | 0.73 | NPBWR1 (0.48) | NPBWR1DGAT1KCNH2SOAT1PTGES | |
| SCHEMBL15245140 | 0.73 | DGAT1 (0.67) | NPBWR1DGAT1KCNH2SOAT1 | |
| SCHEMBL32680254 | 0.73 | DGAT1 (0.44) | NPBWR1AGPAT2DGAT1KCNH2CBFB | |
| SCHEMBL2361306 | 0.72 | AMY1A (0.44) | NPBWR1DGAT1PTGES | |
| SCHEMBL15231992 | 0.72 | DGAT1 (0.47) | NPBWR1DGAT1KCNH2CBFBSOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074387-A1 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2013-05-23 | — | — | WO | disclosed |