Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 5/20 | 0.44 |
| ▸ | PTGES | O14684 | 9/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2360765 | 0.81 | NPBWR1 (0.48) | PTGESNPBWR1PTGS1DGAT1 | |
| SCHEMBL2361397 | 0.80 | DGAT1 (0.51) | PTGESNPBWR1PTGS1DGAT1 | |
| SCHEMBL2342840 | 0.78 | PTGES (0.41) | PTGESNPBWR1PTGS1ORAI1 | |
| SCHEMBL2361302 | 0.78 | PTGES (0.58) | PTGES | |
| SCHEMBL2364623 | 0.77 | USP2 (0.45) | PTGES | |
| SCHEMBL2361250 | 0.77 | AMY1A (0.43) | AMY1APTGESPDE7ADGAT1ORAI1 | |
| SCHEMBL2361260 | 0.77 | PTGES (0.43) | PTGESNPBWR1PTGS1 | |
| SCHEMBL2361475 | 0.77 | DGAT1 (0.43) | AMY1APTGESPTGS1PDE7ADGAT1 | |
| SCHEMBL2361234 | 0.76 | PTGES (0.45) | AMY1APTGESPDE7ADGAT1ORAI1 | |
| SCHEMBL2362184 | 0.76 | AMY1A (0.42) | AMY1APTGESPTGS1PDE7ADGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |