Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.58 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | CLK1 | P49759 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1310500 | 0.83 | KMT2A (0.60) | ALDH1A1GAAUSP2MAPK1DYRK1A | |
| SCHEMBL1310328 | 0.82 | KMT2A (0.55) | ALDH1A1GAAUSP2MAPK1DYRK1A | |
| SCHEMBL1310955 | 0.82 | KMT2A (0.49) | ALDH1A1GAAUSP2MAPK1DYRK1A | |
| SCHEMBL1310766 | 0.79 | GAA (1.00) | ALDH1A1GAAMAPK1DYRK1ADYRK1B | |
| SCHEMBL14972764 | 0.74 | KMT2A (0.66) | ALDH1A1GAAUSP2MAPK1DYRK1A | |
| SCHEMBL14972763 | 0.74 | KMT2A (0.66) | ALDH1A1GAAUSP2MAPK1DYRK1A | |
| SCHEMBL9566863 | 0.74 | DYRK1A (1.00) | ALDH1A1GAAMAPK1DYRK1ADYRK1B | |
| SCHEMBL27260229 | 0.74 | DYRK1A (1.00) | ALDH1A1GAAMAPK1DYRK1ADYRK1B | |
| SCHEMBL18871117 | 0.73 | ALDH1A1 (0.74) | ALDH1A1GAAUSP2MAPTKMT2A | |
| SCHEMBL14972765 | 0.73 | CYP1A2 (0.45) | ALDH1A1GAAUSP2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846125-B2 | Enaminocarbonyl compounds and their use | INSTYTUT CHEMII ORGANICZNEJ, POLSKA AKADEMIA NAUK (PL) | 2014-09-30 | — | — | US | disclosed |
| EP-2391614-B1 | ENAMINOCARBONYL COMPOUNDS AND THEIR USE | INST CHEMII ORGANICZNEJ POLSKA AKADEMIA NAUK (PL) | 2013-05-29 | — | — | EP | disclosed |
| EP-2391614-A1 | ENAMINOCARBONYL COMPOUNDS AND THEIR USE | Instytut Chemii Organicznej, Polska Akademia Nauk (PL) | 2011-12-07 | — | — | EP | disclosed |
| US-20110274803-A1 | ENAMINOCARBONYL COMPOUNDS AND THEIR USE | INSTYTUT CHEMII ORGANICZNEJ, POLSKA AKADEMIA NAUK (PL) | 2011-11-10 | — | — | US | disclosed |
| WO-2010087727-A1 | ENAMINOCARBONYL COMPOUNDS AND THEIR USE | INSTYTUT CHEMII ORGANICZNEJ, POLSKA AKADEMIA NAUK (PL) | 2010-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110274803-A1 | ENAMINOCARBONYL COMPOUNDS AND THEIR USE | TAS2R42, TAS2R41, TAS2R1 | ALDH1A1 1125/4885GAA 1687/4885USP2 3791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.