Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14973944 | 0.85 | ALOX5 (0.44) | TP53ALOX5ALDH1A1TSHRMAPK1 | |
| SCHEMBL14974204 | 0.76 | TP53 (0.43) | TP53ALOX5ALDH1A1TSHRMAPK1 | |
| SCHEMBL14973878 | 0.75 | ALDH1A1 (0.50) | TP53ALDH1A1MAPTCA12CA1 | |
| SCHEMBL14974065 | 0.74 | TSHR (0.44) | TP53ALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL14973686 | 0.73 | ALDH1A1 (0.39) | TP53ALOX5ALDH1A1TSHRMAPK1 | |
| SCHEMBL28198347 | 0.72 | CA12 (0.45) | TP53ALOX5ALDH1A1TSHRMAPK1 | |
| SCHEMBL14974348 | 0.71 | KMT2A (0.45) | ALDH1A1 | |
| SCHEMBL27867316 | 0.71 | ALOX5 (0.56) | TP53ALOX5ALDH1A1MAPTPOLB | |
| SCHEMBL14973615 | 0.69 | MAPT (0.45) | ALDH1A1TSHRMAPK1NPSR1MAPT | |
| SCHEMBL20982037 | 0.69 | POLB (0.40) | ALDH1A1NPSR1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130136794-A1 | HETEROARYL (ALKYL) DITHIOCARBAMATE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | PEKING UNIVERSITY (CN) | 2013-05-30 | — | — | US | claimed |
| US-20130136794-A1 | HETEROARYL (ALKYL) DITHIOCARBAMATE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | PEKING UNIVERSITY (CN) | 2013-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130136794-A1 | HETEROARYL (ALKYL) DITHIOCARBAMATE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | LTK, ERBB2, ABL1 | TP53 62/4885ALOX5 1076/4885ALDH1A1 2942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.