Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14974066 | 0.85 | ALOX5 (0.45) | TSHRALDH1A1MAPK1NPSR1MAPT | |
| SCHEMBL14974204 | 0.74 | TP53 (0.43) | TSHRALDH1A1MAPK1NPSR1MAPT | |
| SCHEMBL14973943 | 0.74 | TP53 (0.43) | TSHRALDH1A1MAPK1NPSR1MAPT | |
| SCHEMBL14973686 | 0.74 | ALDH1A1 (0.39) | TSHRALDH1A1MAPK1NPSR1MAPT | |
| SCHEMBL14973878 | 0.73 | ALDH1A1 (0.50) | ALDH1A1MAPTTP53 | |
| SCHEMBL2838706 | 0.73 | TRPM8 (0.50) | TSHRALDH1A1MAPK1NPSR1MAPT | |
| SCHEMBL5883913 | 0.73 | ALDH1A1 (0.50) | TSHRALDH1A1MAPK1MAPTPOLB | |
| SCHEMBL14973956 | 0.72 | ALDH1A1 (0.51) | ALDH1A1NPSR1MAPT | |
| SCHEMBL20982037 | 0.72 | POLB (0.40) | ALDH1A1NPSR1MAPTPOLB | |
| SCHEMBL21393181 | 0.70 | MAPK1 (0.66) | TSHRALDH1A1MAPK1NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130136794-A1 | HETEROARYL (ALKYL) DITHIOCARBAMATE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | PEKING UNIVERSITY (CN) | 2013-05-30 | — | — | US | claimed |
| US-20130136794-A1 | HETEROARYL (ALKYL) DITHIOCARBAMATE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | PEKING UNIVERSITY (CN) | 2013-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130136794-A1 | HETEROARYL (ALKYL) DITHIOCARBAMATE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | LTK, ERBB2, ABL1 | TSHR 521/4885ALDH1A1 2942/4885MAPK1 551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.