Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.46 |
| ▸ | RELA | Q04206 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | ACR | P10323 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30004969 | 1.00 | NPC1 (0.46) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL17709490 | 1.00 | NPC1 (0.46) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL14916545 | 0.98 | NPC1 (0.43) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL18568355 | 0.94 | MAPT (0.40) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL18150187 | 0.93 | NPC1 (0.47) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL30004023 | 0.93 | NPC1 (0.47) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL13865616 | 0.90 | MAPT (0.36) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL28090966 | 0.90 | TDP1 (0.45) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL13865593 | 0.90 | NPC1 (0.44) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL30726798 | 0.90 | KMT2A (0.41) | NPC1LMNANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190316036-A1 | OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE | JNC CORPORATION (JP) | 2019-10-17 | — | — | US | disclosed |
| US-10308870-B2 | Liquid crystal medium, optical device and liquid crystal compound | JNC CORPORATION (JP) | 2019-06-04 | — | — | US | disclosed |
| CN-104379700-B | Liquid-crystal composition and application thereof, optical element, macromolecule and liquid crystal composite material, mixture and compound | 捷恩智株式会社 | 2018-12-28 | — | — | CN | disclosed |
| EP-2933310-B1 | OCTAHYDRO BINAPHTHYL-BASED CHIRAL COMPOUND-CONTAINING LIQUID-CRYSTAL COMPOSITION AND OPTICAL ELEMENT | JNC CORP (JP) | 2018-06-20 | — | — | EP | disclosed |
| US-9738831-B2 | Optically isotropic liquid crystal composition and optical device | JNC CORPORATION (JP) | 2017-08-22 | — | — | US | disclosed |
| US-9611429-B2 | Liquid crystal medium, optical device and liquid crystal compound | JNC CORPORATION (JP) | 2017-04-04 | — | — | US | disclosed |
| US-9593094-B2 | Liquid crystal medium, optical device, and liquid crystal compound | JNC CORPORATION (JP) | 2017-03-14 | — | — | US | disclosed |
| US-20160304784-A1 | LIQUID CRYSTAL MEDIUM, OPTICAL DEVICE AND LIQUID CRYSTAL COMPOUND | JNC CORPORATION (JP) | 2016-10-20 | — | — | US | disclosed |
| US-9458125-B2 | Octahydro binaphthyl-based chiral compound-containing liquid-crystal composition and optical element | JNC CORPORATION (JP) | 2016-10-04 | — | — | US | disclosed |
| EP-2787058-B1 | OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE | JNC CORP (JP) | 2016-07-27 | — | — | EP | disclosed |
| EP-2933310-A1 | OCTAHYDRO BINAPHTHYL-BASED CHIRAL COMPOUND-CONTAINING LIQUID-CRYSTAL COMPOSITION AND OPTICAL ELEMENT | JNC Corporation (JP) | 2015-10-21 | — | — | EP | disclosed |
| US-20150291548-A1 | OCTAHYDRO BINAPHTHYL-BASED CHIRAL COMPOUND-CONTAINING LIQUID-CRYSTAL COMPOSITION AND OPTICAL ELEMENT | JNC PETROCHEMICAL CORPORATION (JP) | 2015-10-15 | — | — | US | disclosed |
| US-20150240159-A1 | OPTICALLY ISOTROPIC LIQUID CRYSTAL COMPOSITION AND OPTICAL DEVICE | JNC CORPORATION (JP) | 2015-08-27 | — | — | US | disclosed |
| CN-104854217-A | OCTAHYDRO BINAPHTHYL-BASED CHIRAL COMPOUND-CONTAINING LIQUID-CRYSTAL COMPOSITION AND OPTICAL ELEMENT | JNC CORP | 2015-08-19 | — | — | CN | disclosed |
| CN-104334687-A | Optically isotropic liquid crystal medium and optical element | JNC CORP | 2015-02-04 | — | — | CN | disclosed |
| US-8858830-B2 | Optically isotropic liquid crystal medium and optical device | JNC CORPORATION (JP) | 2014-10-14 | — | — | US | disclosed |
| EP-2787058-A1 | OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL ELEMENT | JNC Fibers Corporation (JP) | 2014-10-08 | — | — | EP | disclosed |
| CN-103987809-A | OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE | JNC CORP | 2014-08-13 | — | — | CN | disclosed |
| US-20140132868-A1 | OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2014-05-15 | — | — | US | disclosed |
| US-20130135544-A1 | OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2013-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10308870-B2 | Liquid crystal medium, optical device and liquid crystal compound | OCIAD1, HCN3, HCN1 | NPC1 2023/4885LMNA 2672/4885NFKB1 3067/4885 |
| US-20150291548-A1 | OCTAHYDRO BINAPHTHYL-BASED CHIRAL COMPOUND-CONTAINING LIQUID-CRYSTAL COMPOSITION AND OPTICAL ELEMENT | KLK1, KLK2, SIK1 | NPC1 1371/4885LMNA 2619/4885NFKB1 417/4885 |
| US-20150240159-A1 | OPTICALLY ISOTROPIC LIQUID CRYSTAL COMPOSITION AND OPTICAL DEVICE | SCO2, CNOT1, LEO1 | NPC1 2004/4885LMNA 2934/4885NFKB1 3062/4885 |
| US-20160304784-A1 | LIQUID CRYSTAL MEDIUM, OPTICAL DEVICE AND LIQUID CRYSTAL COMPOUND | HCN1, PIEZO1, NCS1 | NPC1 1894/4885LMNA 2135/4885NFKB1 2741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.