SCHEMBL14975747

SCHEMBL14975747

Clc1nc(Cl)c(I)c(Cl)n1

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
ALOX15 P16050 1/20 0.47
TSHR P16473 1/20 0.47
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19004807 0.80 ALDH1A1 (0.35) ALDH1A1ALOX15TSHR
SCHEMBL10043017 0.80 ALDH1A1 (0.35) ALDH1A1ALOX15TSHR
SCHEMBL2549272 0.80 ALDH1A1 (0.35) ALDH1A1ALOX15TSHR
SCHEMBL22553629 0.73 DPP4 (0.37)
SCHEMBL31512694 0.69 LMNA (0.47)
SCHEMBL218726 0.69 ALDH1A1 (0.54) ALDH1A1ALOX15TSHRCYP1A2
SCHEMBL12036750 0.67 LMNA (0.50) ALDH1A1CYP1A2
SCHEMBL12036809 0.67 PDE4A (0.40) CYP1A2
SCHEMBL29344559 0.67 ALDH1A1 (0.41) ALDH1A1ALOX15TSHR
SCHEMBL1323446 0.67 ALDH1A1 (0.50) ALDH1A1ALOX15TSHRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119968373-A Aromatic heterocyclic compound and preparation method thereof 上海翊石医药科技有限公司 2025-05-09 CN disclosed
WO-2025051214-A1 AROMATIC HETEROCYCLIC COMPOUND AND PREPARATION METHOD THEREFOR 上海翊石医药科技有限公司 2025-03-13 WO disclosed
WO-2019149260-A1 PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF 青岛清原化合物有限公司 2019-08-08 WO disclosed
US-9732100-B2 Preparation of alkaline earth metal-complexed metal bisamides from metal monoamides BAYER CROPSCIENCE AG (DE) 2017-08-15 US disclosed
EP-2956460-B1 PREPARATION OF ALKALINE EARTH METAL-COMPLEXED METAL BISAMIDES FROM METAL MONOAMIDES BAYER CROPSCIENCE AG (DE) 2017-03-22 EP disclosed
CN-104220423-B The metal bisamide of alkaline-earth metal complexing 拜耳知识产权有限责任公司 2016-06-15 CN disclosed
US-9334292-B2 Alkaline earth metal-complexed metal bisamides BAYER CROPSCIENCE AG (DE) 2016-05-10 US disclosed
US-20160016977-A1 ALKALINE EARTH METAL-COMPLEXED METAL BISAMIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-01-21 US disclosed
US-20150368277-A1 PREPARATION OF ALKALINE EARTH METAL-COMPLEXED METAL BISAMIDES FROM METAL MONOAMIDES BAYER CROPSCIENCE AG (DE) 2015-12-24 US disclosed
EP-2956460-A1 PREPARATION OF ALKALINE EARTH METAL-COMPLEXED METAL BISAMIDES FROM METAL MONOAMIDES Bayer CropScience Aktiengesellschaft (DE) 2015-12-23 EP disclosed
EP-2814811-B1 ALKALINE EARTH METAL-COMPLEXED METAL BISAMIDES BAYER IP GMBH (DE) 2015-12-02 EP disclosed
EP-2814811-A1 ALKALINE EARTH METAL-COMPLEXED METAL BISAMIDES Bayer Intellectual Property GmbH (DE) 2014-12-24 EP disclosed
WO-2014124915-A1 PREPARATION OF ALKALINE EARTH METAL-COMPLEXED METAL BISAMIDES FROM METAL MONOAMIDES BAYER CROPSCIENCE AG (DE) 2014-08-21 WO disclosed
WO-2013120911-A1 ALKALINE EARTH METAL-COMPLEXED METAL BISAMIDES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-08-22 WO disclosed
WO-2013078254-A1 BICYCLIC HETEROARYL DERIVATIVES AS KINASE INHIBITORS ARRAY BIOPHARMA INC. (US) 2013-05-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150368277-A1 PREPARATION OF ALKALINE EARTH METAL-COMPLEXED METAL BISAMIDES FROM METAL MONOAMIDES ASH2L, NAAA, MGAM2 ALDH1A1 1597/4885ALOX15 1875/4885TSHR 4076/4885
US-20160016977-A1 ALKALINE EARTH METAL-COMPLEXED METAL BISAMIDES AP1M1, FHIT, AP2M1 ALDH1A1 1035/4885ALOX15 2926/4885TSHR 4365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.