Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.30 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729126 | 0.82 | CYP2A6 (0.41) | ALDH1A1HSD11B1NPC1HPGDRAB9A | |
| SCHEMBL6907358 | 0.81 | CSNK2A1 (0.32) | — | |
| SCHEMBL14975620 | 0.78 | PTPRC (0.36) | ALDH1A1HSD11B1ELANEMAPTPBRM1 | |
| SCHEMBL1982913 | 0.78 | PLA2G7 (0.36) | ALDH1A1HSD11B1ELANENPC1HPGD | |
| SCHEMBL14976063 | 0.78 | C1R (0.31) | ADORA2A | |
| SCHEMBL20961408 | 0.76 | HSD11B1 (0.47) | ALDH1A1MAPK1HSD11B1ELANENPC1 | |
| SCHEMBL3011522 | 0.76 | NOTUM (0.37) | MAPK1TSHRIDO1 | |
| SCHEMBL9004936 | 0.75 | MAPK1 (0.41) | ALDH1A1MAPK1HSD11B1ELANENPC1 | |
| SCHEMBL1768210 | 0.74 | HSD11B1 (0.46) | ALDH1A1MAPK1HSD11B1ELANENPC1 | |
| SCHEMBL8309994 | 0.74 | APP (0.44) | ALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2782565-A1 | USE OF ARYL AND HETARYL CARBOXAMIDES AS ENDOPARASITICIDES | Bayer Intellectual Property GmbH (DE) | 2014-10-01 | — | — | EP | disclosed |
| WO-2013076230-A1 | USE OF ARYL AND HETARYL CARBOXAMIDES AS ENDOPARASITICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-30 | — | — | WO | disclosed |