Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2320148 | 0.85 | PLA2G7 (0.36) | PLA2G7NPC1RAB9ATSHRHPGD | |
| SCHEMBL9729126 | 0.82 | CYP2A6 (0.41) | NPC1RAB9ATSHRHPGDHSD17B10 | |
| SCHEMBL2316025 | 0.82 | PLA2G7 (0.34) | PLA2G7NPC1RAB9ATSHRHPGD | |
| SCHEMBL9040663 | 0.80 | MEN1 (0.35) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL10889222 | 0.80 | ALDH1A1 (0.37) | NPC1RAB9ATSHRHPGDHSD17B10 | |
| SCHEMBL10621165 | 0.79 | NOTUM (0.39) | CASP3HSD11B1NOTUM | |
| SCHEMBL14975950 | 0.78 | ALDH1A1 (0.38) | NPC1RAB9ATSHRHPGDSMN1; SMN2 | |
| SCHEMBL14976063 | 0.78 | C1R (0.31) | — | |
| SCHEMBL14975620 | 0.78 | PTPRC (0.36) | CYP1A2CYP2C19PTGS1PTGS2HSD11B1 | |
| SCHEMBL8309994 | 0.77 | APP (0.44) | TSHRHSD17B10MEN1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011072207-A1 | AZOCYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-06-16 | — | — | WO | disclosed |