Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 7/20 | 0.39 |
| ▸ | HTR1A | P08908 | 6/20 | 0.39 |
| ▸ | HTR2B | P41595 | 6/20 | 0.39 |
| ▸ | HTR5A | P47898 | 6/20 | 0.39 |
| ▸ | HTR6 | P50406 | 6/20 | 0.39 |
| ▸ | HTR1D | P28221 | 5/20 | 0.39 |
| ▸ | HTR1B | P28222 | 5/20 | 0.39 |
| ▸ | HTR2A | P28223 | 5/20 | 0.39 |
| ▸ | HTR2C | P28335 | 4/20 | 0.39 |
| ▸ | HTR1E | P28566 | 4/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729126 | 0.78 | CYP2A6 (0.41) | PTPRCALDH1A1TSHRHSD17B10KDM4E | |
| SCHEMBL4228781 | 0.78 | APP (0.53) | APPHTR7HTR1AHTR2BHTR5A | |
| SCHEMBL11460691 | 0.77 | APP (0.44) | APPPTPRCPTPN1HTR7HTR1A | |
| SCHEMBL1982913 | 0.77 | PLA2G7 (0.36) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL9040663 | 0.76 | MEN1 (0.35) | KDM4EMEN1MAPTKMT2A | |
| SCHEMBL10607765 | 0.75 | APP (0.47) | APPPTPRCPTPN1HTR7HTR1A | |
| SCHEMBL14975620 | 0.74 | PTPRC (0.36) | PTPRCPTPN1ALDH1A1MAPTTDP1 | |
| SCHEMBL14975950 | 0.74 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPT | |
| SCHEMBL14976063 | 0.74 | C1R (0.31) | — | |
| SCHEMBL4225117 | 0.73 | APP (0.52) | APPHTR7HTR1AHTR2BHTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892795-A1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997038992-A1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-10-23 | — | — | WO | disclosed |