Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4758150 | 0.88 | HPGD (0.63) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL4758147 | 0.88 | HPGD (0.63) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL14977076 | 0.82 | MEN1 (0.52) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL10144825 | 0.77 | MAPK1 (0.67) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL14397665 | 0.76 | KMT2A (0.60) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL24862898 | 0.76 | NPC1 (0.63) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL5325179 | 0.75 | NR1H4 (0.55) | MEN1KMT2AALDH1A1ADRB1ADRB3 | |
| SCHEMBL5326665 | 0.75 | NR1H4 (0.55) | MEN1KMT2AALDH1A1ADRB1ADRB3 | |
| SCHEMBL5324896 | 0.75 | NR1H4 (0.55) | MEN1KMT2AALDH1A1ADRB1ADRB3 | |
| SCHEMBL14976803 | 0.75 | KCNA3 (0.60) | POLBNPC1RAB9AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | disclosed |