Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 2/20 | 0.48 |
| ▸ | ACACB | O00763 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5324896 | 1.00 | NR1H4 (0.55) | NR1H4PPARGPPARAADRB1ADRB3 | |
| SCHEMBL5325179 | 1.00 | NR1H4 (0.55) | NR1H4PPARGPPARAADRB1ADRB3 | |
| SCHEMBL5326505 | 0.85 | NR1H4 (0.49) | NR1H4PPARGPPARAADRB1ADRB3 | |
| SCHEMBL14397275 | 0.85 | NR1H4 (0.49) | NR1H4PPARGPPARAADRB1ADRB3 | |
| SCHEMBL5327174 | 0.84 | ALDH1A1 (0.51) | PPARAADRB3ACACBALDH1A1PSMB5 | |
| SCHEMBL5325174 | 0.83 | ALDH1A1 (0.70) | PPARGACACBALDH1A1PSMB5DNMT3A | |
| SCHEMBL14397665 | 0.83 | KMT2A (0.60) | ACACBALDH1A1MEN1KMT2A | |
| SCHEMBL18998085 | 0.82 | USP2 (0.57) | NR1H4PPARGPPARAADRB1ADRB3 | |
| SCHEMBL5324280 | 0.81 | ROCK2 (0.49) | ACACBALDH1A1PSMB5MEN1KMT2A | |
| SCHEMBL14398212 | 0.81 | ALDH1A1 (0.48) | NR1H4PPARAACACBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |