Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 2/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethenzamide SCHEMBL25624 | 0.89 | MAPT (0.68) | HTTMEN1KMT2ACYP3A4LMNA | |
| Ethenzamide SCHEMBL27612766 | 0.89 | MAPT (0.68) | HTTMEN1KMT2ACYP3A4LMNA | |
| Ethenzamide SCHEMBL5401172 | 0.87 | MAPT (0.66) | HTTMEN1KMT2ACYP3A4LMNA | |
| Ethenzamide SCHEMBL4379591 | 0.87 | MAPT (0.66) | HTTMEN1KMT2ACYP3A4LMNA | |
| Ethenzamide SCHEMBL22163775 | 0.87 | MAPT (0.66) | HTTMEN1KMT2ACYP3A4LMNA | |
| Ethenzamide SCHEMBL5382992 | 0.83 | MAPT (0.60) | HTTMEN1KMT2ACYP3A4LMNA | |
| Hydrochloric Acid SCHEMBL9868741 | 0.81 | HCRTR1 (0.54) | HTTMEN1KMT2ALMNAMAPT | |
| SCHEMBL7932427 | 0.80 | MEN1 (0.60) | HTTMEN1KMT2ACYP3A4LMNA | |
| SCHEMBL15163056 | 0.80 | HTT (0.65) | HTTMEN1KMT2ACYP3A4LMNA | |
| SCHEMBL13763533 | 0.78 | HTT (0.71) | HTTMEN1KMT2ACYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013075680-A1 | A METHOD FOR THE PREPARATION AND ISOLATION OF SALTS OF VARDENAFIL WITH ACIDS | ZENTIVA, K.S. (CZ) | 2013-05-30 | — | — | WO | disclosed |