Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 4/20 | 0.37 |
| ▸ | CNR2 | P34972 | 4/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | PLTP | P55058 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14986306 | 0.93 | MAPK14 (0.37) | ABL1MAPK14MAPTNAMPT | |
| SCHEMBL14977606 | 0.92 | MAPK14 (0.41) | ABL1DGAT2MAPK14NPC1RAB9A | |
| SCHEMBL14977581 | 0.89 | MAPK14 (0.39) | ABL1MAPK14MAPTNAMPT | |
| SCHEMBL14977569 | 0.89 | MAPK14 (0.37) | ABL1DGAT2MAPK14MAPT | |
| SCHEMBL14977247 | 0.88 | MAPK14 (0.38) | CNR2MAPK14MAPT | |
| SCHEMBL14977604 | 0.87 | MAPK14 (0.36) | ABL1DGAT2MAPK14MAPT | |
| SCHEMBL14977707 | 0.87 | PPARG (0.39) | DGAT2MAPK14NPC1MAPT | |
| SCHEMBL14977601 | 0.86 | CYP2C8 (0.38) | ABL1MAPK14NAMPT | |
| SCHEMBL14986287 | 0.86 | MAPK14 (0.39) | ABL1MAPK14NPC1RAB9AMAPT | |
| SCHEMBL14977841 | 0.86 | MAPK14 (0.35) | ABL1DGAT2MAPK14MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | claimed |
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | disclosed |
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | disclosed |