Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 8/20 | 0.41 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.36 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14977610 | 0.93 | DGAT2 (0.38) | MAPK14DGAT2ACSS2NPC1RAB9A | |
| SCHEMBL14977138 | 0.93 | MAPK14 (0.37) | MAPK14NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL14977569 | 0.92 | MAPK14 (0.37) | MAPK14DGAT2ACSS2CYP2C8KCNH2 | |
| SCHEMBL14977581 | 0.92 | MAPK14 (0.39) | MAPK14ACSS2CYP2C8KCNH2MAPT | |
| SCHEMBL14977313 | 0.92 | ABL1 (0.41) | MAPK14DGAT2NPC1RAB9AMAPT | |
| SCHEMBL14986306 | 0.92 | MAPK14 (0.37) | MAPK14ACSS2CYP2C8KCNH2MAPT | |
| SCHEMBL14977598 | 0.91 | CNR1 (0.42) | MAPK14NPC1RAB9AALDH1A1 | |
| SCHEMBL14977625 | 0.91 | RIPK2 (0.36) | MAPK14NPC1RAB9AMAPTKDM4E | |
| SCHEMBL14977247 | 0.91 | MAPK14 (0.38) | MAPK14ACSS2CYP2C8KCNH2MAPT | |
| SCHEMBL14977618 | 0.91 | LHCGR (0.41) | MAPK14DGAT2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | claimed |
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | disclosed |