Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.35 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14977569 | 0.96 | MAPK14 (0.37) | MAPK14ACSS2DGAT2ABL1MAPT | |
| SCHEMBL14977604 | 0.94 | MAPK14 (0.36) | MAPK14ACSS2DGAT2ABL1MAPT | |
| SCHEMBL14977776 | 0.92 | SUCNR1 (0.37) | MAPK14ACSS2B3GNT2MAPTMALT1 | |
| SCHEMBL14977707 | 0.92 | PPARG (0.39) | MAPK14ACSS2DGAT2MAPTKDM4E | |
| SCHEMBL14977598 | 0.89 | CNR1 (0.42) | MAPK14TP53POLBALDH1A1MALT1 | |
| SCHEMBL14977606 | 0.89 | MAPK14 (0.41) | MAPK14ACSS2DGAT2ABL1MAPT | |
| SCHEMBL14977623 | 0.88 | PPARG (0.39) | ACSS2DGAT2TP53MAPTKDM4E | |
| SCHEMBL14977379 | 0.88 | DGAT2 (0.42) | ACSS2DGAT2TP53MAPTKDM4E | |
| SCHEMBL14977601 | 0.87 | CYP2C8 (0.38) | MAPK14ABL1SMN1; SMN2 | |
| SCHEMBL14977778 | 0.87 | ROCK2 (0.39) | MAPK14ABL1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | claimed |
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | disclosed |