Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.36 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14977569 | 0.98 | MAPK14 (0.37) | MAPK14ACSS2MAPTDGAT1ABL1 | |
| SCHEMBL14977841 | 0.94 | MAPK14 (0.35) | MAPK14ACSS2MAPTABL1DGAT2 | |
| SCHEMBL14977707 | 0.94 | PPARG (0.39) | MAPK14ACSS2MAPTDGAT2CYP2C8 | |
| SCHEMBL14986303 | 0.92 | ROCK2 (0.37) | MAPK14ACSS2PPARG | |
| SCHEMBL14977606 | 0.90 | MAPK14 (0.41) | MAPK14ACSS2MAPTABL1DGAT2 | |
| SCHEMBL14977138 | 0.88 | MAPK14 (0.37) | MAPK14MAPT | |
| SCHEMBL14977601 | 0.88 | CYP2C8 (0.38) | MAPK14ABL1CYP2C8KCNH2 | |
| SCHEMBL14977778 | 0.88 | ROCK2 (0.39) | MAPK14MAPTABL1 | |
| SCHEMBL14977581 | 0.88 | MAPK14 (0.39) | MAPK14ACSS2MAPTABL1CYP2C8 | |
| SCHEMBL14976867 | 0.88 | ROCK2 (0.38) | MAPK14ACSS2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | claimed |
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | disclosed |
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | disclosed |