Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | DCK | P27707 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14977224 | 0.83 | KIT (0.39) | MAPTTHRBRXFP1LMNAKMT2A | |
| SCHEMBL14977691 | 0.82 | CYP2C8 (0.43) | MAPK14 | |
| SCHEMBL14977765 | 0.80 | CYP2C8 (0.47) | MAPK14 | |
| SCHEMBL14976444 | 0.75 | CSNK1D (0.39) | THRB | |
| SCHEMBL14986287 | 0.75 | MAPK14 (0.39) | MAPTTHRBTP53MAPK14LMNA | |
| SCHEMBL14977610 | 0.74 | DGAT2 (0.38) | MAPTTHRBMAPK14LMNA | |
| SCHEMBL14977606 | 0.74 | MAPK14 (0.41) | MAPTMAPK14 | |
| SCHEMBL14977839 | 0.73 | WDR5 (0.44) | MAPTTHRBTP53MAPK11MAPK14 | |
| SCHEMBL14977538 | 0.72 | KDM4E (0.42) | MAPTTHRBTP53RXFP1LMNA | |
| SCHEMBL2466021 | 0.72 | PIK3CG (0.45) | MAPK14MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | claimed |
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | disclosed |