Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14977611 | 0.81 | DHODH (0.64) | NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL14977583 | 0.80 | RAB9A (0.68) | NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL14977409 | 0.80 | RAB9A (0.45) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL14977161 | 0.80 | RAB9A (0.64) | ATMNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL14977713 | 0.80 | RAB9A (0.64) | ATMNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL14985331 | 0.80 | NPC1 (0.67) | ATMNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL14977788 | 0.79 | DHODH (0.69) | KMT2AMEN1GAA | |
| SCHEMBL14977705 | 0.79 | MEN1 (0.63) | NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL14977672 | 0.79 | MEN1 (0.58) | NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL14985372 | 0.78 | KMT2A (0.57) | NPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013078413-A1 | MODULATORS OF LIPID STORAGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-05-30 | — | — | WO | disclosed |
| WO-2013078413-A1 | MODULATORS OF LIPID STORAGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-05-30 | — | — | WO | disclosed |