Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.33 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14976867 | 0.94 | ROCK2 (0.38) | PPARGROCK2ROCK1ACSS2DDR2 | |
| SCHEMBL14986303 | 0.94 | ROCK2 (0.37) | PPARGROCK2ROCK1ACSS2DDR2 | |
| SCHEMBL14977841 | 0.92 | MAPK14 (0.35) | MAPTMALT1ACSS2SMN1; SMN2B3GNT2 | |
| SCHEMBL14977707 | 0.92 | PPARG (0.39) | PPARGROCK2ROCK1MAPTKMT2A | |
| SCHEMBL14977598 | 0.90 | CNR1 (0.42) | SUCNR1MALT1SMN1; SMN2NR4A2MAPK14 | |
| SCHEMBL14977569 | 0.88 | MAPK14 (0.37) | PPARGMAPTACSS2MAPK14 | |
| SCHEMBL14977688 | 0.88 | PPARG (0.38) | PPARGROCK2ROCK1MAPTKMT2A | |
| SCHEMBL14977379 | 0.87 | DGAT2 (0.42) | PPARGROCK2ROCK1MAPTKMT2A | |
| SCHEMBL14977623 | 0.87 | PPARG (0.39) | PPARGROCK2ROCK1MAPTKMT2A | |
| SCHEMBL14977625 | 0.87 | RIPK2 (0.36) | MAPTMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | disclosed |