Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | LHCGR | P22888 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14976867 | 0.93 | ROCK2 (0.38) | PPARGMAPK14ROCK2ROCK1TACR3 | |
| SCHEMBL14977707 | 0.92 | PPARG (0.39) | PPARGMAPK14ROCK2ROCK1MAPT | |
| SCHEMBL14977618 | 0.91 | LHCGR (0.41) | CSNK1EMAPK14LHCGRMAPTTP53 | |
| SCHEMBL14986303 | 0.89 | ROCK2 (0.37) | PPARGMAPK14ROCK2ROCK1TACR3 | |
| SCHEMBL14977569 | 0.88 | MAPK14 (0.37) | PPARGMAPK14MAPT | |
| SCHEMBL14977776 | 0.88 | SUCNR1 (0.37) | PPARGMAPK14ROCK2ROCK1MAPT | |
| SCHEMBL14977604 | 0.86 | MAPK14 (0.36) | PPARGMAPK14MAPT | |
| SCHEMBL14977623 | 0.86 | PPARG (0.39) | PPARGROCK2ROCK1MAPTTP53 | |
| SCHEMBL14977625 | 0.85 | RIPK2 (0.36) | MAPK14MAPT | |
| SCHEMBL14977778 | 0.85 | ROCK2 (0.39) | MAPK14ROCK2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | disclosed |
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | disclosed |