Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966358 | 0.88 | TP53 (0.50) | BTKPDE10ATP53KDM4E | |
| SCHEMBL14978752 | 0.87 | BTK (0.41) | BTKPDE10ABDKRB1ALDH1A1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL14970184 | 0.84 | PDE10A (0.38) | BTKPDE10ABDKRB1ALDH1A1CYP1A2 | |
| SCHEMBL14969683 | 0.79 | CYP2C9 (0.43) | BTKALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16169605 | 0.73 | TP53 (0.61) | TP53KDM4E | |
| SCHEMBL20236498 | 0.73 | ADRB2 (0.50) | ALDH1A1CYP2C9LMNAADRB2 | |
| SCHEMBL3652239 | 0.72 | RBP4 (0.52) | ALDH1A1CYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL14969496 | 0.72 | TP53 (0.64) | TP53LMNAKDM4E | |
| SCHEMBL14978690 | 0.72 | GPR119 (0.42) | BTKTP53RORC | |
| SCHEMBL14978691 | 0.72 | TP53 (0.37) | TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074641-A1 | PIPERIDINYL- SUBSTITUTED CYCLIC UREAS AS GPR119 MODULATORS | ARRAY BIOPHARMA INC. (US) | 2013-05-23 | — | — | WO | disclosed |