SCHEMBL14979413

SCHEMBL14979413

CB(O)c1ccc2ccccc2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.68
CA2 P00918 2/20 0.68
UGT2B7 P16662 1/20 0.47
CYP2A6 P11509 6/20 0.44
CYP1A2 P05177 4/20 0.44
TDP1 Q9NUW8 1/20 0.44
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
HTR2A P28223 1/20 0.38
HTR2C P28335 1/20 0.38
HTR2B P41595 1/20 0.38
EPHX1 P07099 1/20 0.38
ALOX5 P09917 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16547259 0.84 CA2 (0.64) CA1CA2
SCHEMBL9945976 0.81 CA1 (0.60) CA1CA2UGT2B7CYP2A6CYP1A2
SCHEMBL23150 0.81 CA1 (1.00) CA1CA2CYP2A6CYP1A2TDP1
SCHEMBL29612616 0.81 CA1 (1.00) CA1CA2CYP2A6CYP1A2TDP1
SCHEMBL23095256 0.81 CA1 (0.60) CA1CA2UGT2B7CYP2A6CYP1A2
Hydrochloric Acid SCHEMBL27818196 0.79 CA1 (0.95) CA1CA2CYP2A6CYP1A2TDP1
SCHEMBL21076143 0.77 CA1 (0.61) CA1CA2UGT2B7CYP2A6CYP1A2
SCHEMBL22635041 0.76 CA1 (0.65) CA1CA2UGT2B7CYP2A6CYP1A2
SCHEMBL1477665 0.75 CA1 (0.65) CA1CA2CYP2A6CYP1A2TDP1
SCHEMBL28601040 0.75 CA1 (0.77) CA1CA2UGT2B7CYP2A6CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9748487-B2 Polymers based on naphthodiones BASF SE (DE) 2017-08-29 US disclosed
US-9698348-B2 Polymers based on fused diketopyrrolopyrroles BASF SE (DE) 2017-07-04 US disclosed
US-20160181534-A1 POLYMERS BASED ON FUSED DIKETOPYRROLOPYRROLES CLAP CO., LTD. (KR) 2016-06-23 US disclosed
US-9359470-B2 Dithienobenzofuran polymers and small molecules for electronic application BASF SE (DE) 2016-06-07 US disclosed
US-20160049588-A1 POLYMERS BASED ON NAPHTHODIONES BASF SE (DE) 2016-02-18 US disclosed
US-9240551-B2 Polymers based on benzodiones BASF SE (DE) 2016-01-19 US disclosed
US-20150132887-A1 DITHIENOBENZOFURAN POLYMERS AND SMALL MOLECULES FOR ELECTRONIC APPLICATION BASF SE (DE) 2015-05-14 US disclosed
US-20150111337-A1 PHENANTHRO[9,10-B]FURAN POLYMERS AND SMALL MOLECULES FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2015-04-23 US disclosed
US-20140302637-A1 POLYMERS BASED ON BENZODIONES BASF SE (DE) 2014-10-09 US disclosed
WO-2013073859-A1 NOVEL ORGANIC ELECTROLUMINESCENCE COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2013-05-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160049588-A1 POLYMERS BASED ON NAPHTHODIONES CCND2, CCND1, PCNA CA1 4801/4885CA2 4727/4885UGT2B7 1623/4885
US-20160181534-A1 POLYMERS BASED ON FUSED DIKETOPYRROLOPYRROLES PIN1, IK, FTO CA1 4402/4885CA2 3257/4885UGT2B7 3891/4885
US-20150132887-A1 DITHIENOBENZOFURAN POLYMERS AND SMALL MOLECULES FOR ELECTRONIC APPLICATION DDT, F12, ETFB CA1 3697/4885CA2 2933/4885UGT2B7 2816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.