Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ERN1 | O75460 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13043499 | 0.91 | ALDH1A1 (0.34) | ALDH1A1ERN1L3MBTL1LMNACYP1A2 | |
| SCHEMBL3744230 | 0.89 | ERN1 (0.33) | ALDH1A1ERN1 | |
| SCHEMBL13079249 | 0.89 | ALDH1A1 (0.38) | ALDH1A1ERN1KDM4EL3MBTL1TUBB1 | |
| SCHEMBL3754539 | 0.88 | PREP (0.35) | ALDH1A1ERN1TUBB1 | |
| SCHEMBL13078743 | 0.79 | PREP (0.35) | ALDH1A1ERN1TUBB1 | |
| SCHEMBL13079722 | 0.79 | ERN1 (0.33) | ALDH1A1ERN1 | |
| SCHEMBL28803580 | 0.78 | ALDH1A1 (0.53) | ALDH1A1ERN1TUBB1LMNACYP1A2 | |
| SCHEMBL13078747 | 0.69 | ERN1 (0.60) | ALDH1A1ERN1LMNACYP1A2CYP2C9 | |
| SCHEMBL118322 | 0.65 | KDM4E (0.54) | ALDH1A1ERN1KDM4EL3MBTL1TUBB1 | |
| SCHEMBL3924348 | 0.64 | ALDH1A1 (0.71) | ALDH1A1ERN1KDM4EL3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450365-B2 | Efficient synthesis of galanthamine | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-05-28 | — | — | US | disclosed |