Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.35 |
| ▸ | ERN1 | O75460 | 2/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13078743 | 0.92 | PREP (0.35) | PREPERN1TUBB1ALDH1A1 | |
| SCHEMBL14980271 | 0.88 | ALDH1A1 (0.38) | ERN1TUBB1ALDH1A1 | |
| SCHEMBL3744230 | 0.88 | ERN1 (0.33) | ERN1ALDH1A1 | |
| SCHEMBL13043499 | 0.84 | ALDH1A1 (0.34) | ERN1ALDH1A1 | |
| SCHEMBL13079722 | 0.78 | ERN1 (0.33) | ERN1ALDH1A1 | |
| SCHEMBL13079249 | 0.78 | ALDH1A1 (0.38) | ERN1TUBB1ALDH1A1 | |
| SCHEMBL3744167 | 0.75 | ERN1 (0.43) | PREPERN1ALDH1A1 | |
| SCHEMBL5139277 | 0.68 | ALDH1A1 (0.40) | ERN1ALDH1A1DRD2 | |
| SCHEMBL22230872 | 0.67 | ALDH1A1 (0.40) | ERN1TUBB1ALDH1A1 | |
| SCHEMBL5383976 | 0.67 | ALDH1A1 (0.63) | ERN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450365-B2 | Efficient synthesis of galanthamine | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-05-28 | — | — | US | disclosed |
| US-8362283-B2 | Cross-conjugated 2,5-cyclohexadienone and related synthesis methods | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-01-29 | — | — | US | disclosed |
| US-8293927-B2 | Efficient synthesis of morphine and codeine | BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-10-23 | — | — | US | disclosed |
| US-20100292475-A1 | Efficient Synthesis Of Morphine And Codeine | BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292475-A1 | Efficient Synthesis Of Morphine And Codeine | OPRK1, OPRM1, OPRL1 | PREP 2012/4885ERN1 1030/4885TUBB1 2874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.