Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 5/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14980271 | 0.91 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1LMNAMAPTERN1 | |
| SCHEMBL3744230 | 0.85 | ERN1 (0.33) | ALDH1A1ERN1 | |
| SCHEMBL3754539 | 0.84 | PREP (0.35) | ALDH1A1ERN1 | |
| SCHEMBL13079249 | 0.80 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1LMNAMAPTERN1 | |
| SCHEMBL13078743 | 0.75 | PREP (0.35) | ALDH1A1ERN1 | |
| SCHEMBL13079722 | 0.74 | ERN1 (0.33) | ALDH1A1ERN1 | |
| SCHEMBL13043498 | 0.69 | ERN1 (0.50) | ERN1 | |
| SCHEMBL28803580 | 0.67 | ALDH1A1 (0.53) | ALDH1A1LMNAMAPTERN1CYP1A2 | |
| SCHEMBL7922716 | 0.65 | ERN1 (0.53) | ALDH1A1L3MBTL1LMNAMAPTHPGD | |
| SCHEMBL12816057 | 0.65 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1LMNAERN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450365-B2 | Efficient synthesis of galanthamine | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-05-28 | — | — | US | disclosed |
| US-8362283-B2 | Cross-conjugated 2,5-cyclohexadienone and related synthesis methods | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-01-29 | — | — | US | disclosed |
| US-8293927-B2 | Efficient synthesis of morphine and codeine | BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-10-23 | — | — | US | disclosed |
| US-20100292466-A1 | Efficient Synthesis Of Galanthamine | BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM | 2010-11-18 | — | — | US | disclosed |
| US-20100292475-A1 | Efficient Synthesis Of Morphine And Codeine | BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM | 2010-11-18 | — | — | US | disclosed |
| US-20100292489-A1 | Cross-conjugated 2,5-cyclohexadienone and related synthesis methods | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292466-A1 | Efficient Synthesis Of Galanthamine | GALR2, GALR1, OPRK1 | ALDH1A1 1200/4885L3MBTL1 1475/4885LMNA 4169/4885 |
| US-20100292489-A1 | Cross-conjugated 2,5-cyclohexadienone and related synthesis methods | OPRK1, GALR2, OPRM1 | ALDH1A1 596/4885L3MBTL1 2407/4885LMNA 3681/4885 |
| US-20100292475-A1 | Efficient Synthesis Of Morphine And Codeine | OPRK1, OPRM1, OPRL1 | ALDH1A1 1044/4885L3MBTL1 1198/4885LMNA 4239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.