SCHEMBL1498028

SCHEMBL1498028

CCN(O)Cc1cc(N)ccc1O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.73
ACHE P22303 3/20 0.71
ALDH1A1 P00352 5/20 0.47
TDP1 Q9NUW8 4/20 0.47
POLB P06746 3/20 0.47
KDM4E B2RXH2 3/20 0.47
MEN1 O00255 3/20 0.47
THRB P10828 3/20 0.47
KMT2A Q03164 3/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
RECQL P46063 3/20 0.47
MAPT P10636 2/20 0.47
HKDC1 Q2TB90 2/20 0.47
MAPK1 P28482 2/20 0.47
APEX1 P27695 1/20 0.47
HTT P42858 1/20 0.47
CACNA1B Q00975 1/20 0.47
APBA1 Q02410 1/20 0.47
MCL1 Q07820 1/20 0.47
JAK2 O60674 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3336998 0.98 ACHE (0.74) PRKCIACHEALDH1A1TDP1POLB
Hydrochloric Acid SCHEMBL29355056 0.98 ACHE (0.74) PRKCIACHEALDH1A1TDP1POLB
SCHEMBL111109 0.85 PRKCI (1.00) PRKCIACHEALDH1A1TDP1POLB
SCHEMBL29565648 0.85 PRKCI (1.00) PRKCIACHEALDH1A1TDP1POLB
Hydrochloric Acid SCHEMBL1998660 0.83 ACHE (1.00) PRKCIACHEALDH1A1TDP1POLB
Hydrochloric Acid SCHEMBL1998656 0.83 ACHE (1.00) PRKCIACHEALDH1A1TDP1POLB
SCHEMBL5270782 0.79 PRKCI (0.86) PRKCIACHEALDH1A1TDP1POLB
SCHEMBL3338265 0.79 PRKCI (0.69) PRKCIACHEALDH1A1TDP1POLB
SCHEMBL29834174 0.79 PRKCI (0.69) PRKCIACHEALDH1A1TDP1POLB
SCHEMBL440146 0.78 PRKCI (0.68) PRKCIACHEALDH1A1TDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10639257-B2 Composition for colouring keratin fibres BEAUTY & BUSINESS S.P.A. (IT) 2020-05-05 US claimed
US-20190117541-A1 COMPOSITION FOR COLOURING KERATIN FIBRES BEAUTY & BUSINESS S.P.A. (IT) 2019-04-25 US claimed
US-9993413-B2 Keratin fibre dyeing composition BEAUTY & BUSINESS S.P.A. (IT) 2018-06-12 US claimed
US-20170258695-A1 KERATIN FIBRE DYEING COMPOSITION BEAUTY & BUSINESS S.P.A. (IT) 2017-09-14 US claimed
US-6638321-B1 Oxidation color dyes for hair from aniline compounds L'OREAL (FR) 2003-10-28 US claimed
US-6602303-B2 And a combination of an alkoxylated or glycerolated fatty alcohol and a hydroxylated L'OREAL S.A. (FR) 2003-08-05 US claimed
US-6565614-B1 Mixture containing quaternary ammonium compound L'OREAL (FR) 2003-05-20 US claimed
US-6537328-B1 Hair dye L'OREAL S.A. (FR) 2003-03-25 US claimed
US-20030000026-A9 Composition for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one cationic amphiphilic polymer, and dyeing methods L'OREAL S.A. (FR) 2003-01-02 US claimed
US-20020046431-A1 Composition for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one cationic amphiphilic polymer, and dyeing methods LAURENT FLORENCE (FR) 2002-04-25 US claimed
EP-4548908-A1 PERMANENT OXIDATIVE HAIR-COLOURING COMPOSITIONS Beauty & Business SpA (IT) 2025-05-07 EP disclosed
US-20250134788-A1 PERMANENT OXIDATIVE HAIR-COLORING COMPOSITIONS BEAUTY & BUSINESS S.P.A. (IT) 2025-05-01 US disclosed
EP-4362889-A1 COMPOSITION COMPRISING AT LEAST ONE OXIDATION DYE, 1,3-PROPANEDIOL, AT LEAST ONE ALKALINE AGENT AND AT LEAST ONE FATTY SUBSTANCE L'OREAL (FR) 2024-05-08 EP disclosed
EP-4362902-A1 COMPOSITIONS CONTAINING DIRECT DYES FOR IMPARTING COLOR AND TONE TO THE HAIR L'OREAL (FR) 2024-05-08 EP disclosed
EP-4362891-A1 COMPOSITION COMPRISING AT LEAST ONE PARTICULAR COUPLER, AT LEAST ONE PARTICULAR OXIDATION BASE, AT LEAST ONE FATTY SUBSTANCE AND AT LEAST ONE ANIONIC POLYSACCHARIDE L'OREAL (FR) 2024-05-08 EP disclosed
EP-0970041-A1 NEW DIAMINOALKANE AND OXIDATION DYEING AGENT Hans Schwarzkopf GmbH & Co. KG (DE) 2000-01-12 EP disclosed
WO-1999029285-A2 HAIR COLORANT PREPARATION HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1999-06-17 WO disclosed
WO-1998001418-A1 NEW DIAMINOALKANE AND OXIDATION DYEING AGENT HANS SCHWARZKOPF GMBH & CO.KG (DE) 1998-01-15 WO disclosed
EP-0591373-A1 META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD. OREAL (FR) 1994-04-13 EP disclosed
WO-1993000066-A1 META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD L'OREAL (FR) 1993-01-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030000026-A9 Composition for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one cationic amphiphilic polymer, and dyeing methods KRT18, ACAD10, OAT PRKCI 743/4885ACHE 3689/4885ALDH1A1 115/4885
US-20020046431-A1 Composition for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one cationic amphiphilic polymer, and dyeing methods KRT18, ACAD10, OAT PRKCI 743/4885ACHE 3689/4885ALDH1A1 115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.