SCHEMBL1498036

SCHEMBL1498036

C#CC(=C)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.44
MAOB P27338 6/20 0.44
CES2 O00748 2/20 0.38
CES1 P23141 2/20 0.38
DAO P14920 1/20 0.38
TSHR P16473 1/20 0.38
NAPRT Q6XQN6 1/20 0.38
ALDH1A1 P00352 1/20 0.38
AKT1 P31749 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
XBP1 P17861 1/20 0.35
ATM Q13315 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13567786 0.86 SMN1; SMN2 (0.43) ALDH1A1MEN1KMT2ALMNAMAPT
SCHEMBL13567787 0.81 PARP10 (0.48) MAOATSHRSMN1; SMN2
SCHEMBL9119892 0.78 MAPT (0.42) MAOAMAOBCES2CES1DAO
SCHEMBL330617 0.74 ALDH1A1 (0.42) MAOAMAOBCES2CES1DAO
SCHEMBL146099 0.74 CES1 (0.43) CES2CES1DAOTSHRNAPRT
SCHEMBL6865935 0.74 MAOA (0.41) MAOAMAOBCES2CES1DAO
SCHEMBL464697 0.74
SCHEMBL11880182 0.72 CES1 (0.41) MAOAMAOBCES2CES1DAO
SCHEMBL2106149 0.72 CES1 (0.41) MAOAMAOBCES2CES1DAO
Methane SCHEMBL10894930 0.72 ALDH1A1 (0.41) MAOAMAOBCES2CES1DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 354 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025123334-A1 TWO-PART SILICONE COMPOSITION AND FOAM SEALANT AND ASSEMBLY MADE THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-06-19 WO claimed
CN-116685648-A Composition for silicone release coating and release film comprising same HRS株式会社 2023-09-01 CN claimed
CN-116635497-A Composition for silicone adhesive coating and adhesive film comprising same HRS株式会社 2023-08-22 CN claimed
CN-105504825-B Silicone rubber composition and method for producing same 现代摩比斯株式会社 2021-01-08 CN claimed
US-9963577-B2 Silicone rubber composition and manufacturing method thereof HYUNDAI MOBIS CO., LTD. (KR) 2018-05-08 US claimed
US-20160102191-A1 SILICONE RUBBER COMPOSITION AND MANUFACTURING METHOD THEREOF GRACE CONTINENTAL KOREA CO., LTD. (KR) 2016-04-14 US claimed
EP-1004632-B1 Silicone composition for forming cured release films DOW CORNING TORAY SILICONE (JP) 2003-12-10 EP claimed
US-6586535-B1 Polysiloxanes containing alkenyl groups DOW CORNING CORPORATION 2003-07-01 US claimed
US-6489407-B1 SOLVENT-FREE (CO-)POLYSILOXANES USED AS ANTISTICK AGENTS FOR LAMINATION OF PAPER SUBSTRATES DOW CORNING CORPORATION 2002-12-03 US claimed
US-6300426-B1 IMPARTS TO THE SURFACES OF VARIOUS SUBSTRATES, SUCH AS PAPER, SYNTHETIC RESIN FILM, OR METAL FOIL, RELEASE PROPERTIES RELATIVE TO TACKY SUBSTANCES DOW CORNING TORAY SILICONE COMPANY, LTD. (JP) 2001-10-09 US claimed
US-6124419-A A RELEASE MODIFIER COMPRISING AN ALKENYL FUNCTIONAL POLYORGANOSILOXANE AND A BRANCHED OLEFIN USEFUL IN RELEASE PRESSURE SENSITIVE ADHESIVES FROM A VARIETY OF SUBSTRATES DOW CORNING, LIMITED (GB) 2000-09-26 US claimed
EP-1004632-A1 Silicone composition for forming cured release films Dow Corning Toray Silicone Company, Ltd. (JP) 2000-05-31 EP claimed
EP-0980903-A2 Release modifier compositions DOW CORNING CORPORATION (US) 2000-02-23 EP claimed
US-4631247-A Acetylene compounds as shelf life improvers for photoresist compositions containing organic iodides HERCULES INCORPORATED (US) 1986-12-23 US claimed
US-20260132325-A1 THERMALLY CONDUCTIVE SILICONE COMPOSITION DOW SILICONES CORP (US) 2026-05-14 US disclosed
CN-122011778-A Gel-type thermal interface material 霍尼韦尔国际公司 2026-05-12 CN disclosed
EP-4716962-A1 HIGHLY THERMALLY CONDUCTIVE HYBRID THERMAL INTERFACE MATERIAL Solstice Advanced Materials US, Inc. (US) 2026-04-01 EP disclosed
US-4631247-A Acetylene compounds as shelf life improvers for photoresist compositions containing organic iodides HERCULES INCORPORATED (US) 1986-12-23 US disclosed
EP-0094185-A2 Use of peelable film-forming organopolysiloxane compositions Toray Silicone Company Limited (JP) 1983-11-16 EP disclosed
EP-0091291-A2 Room temperature stable, heat activated organopolysiloxane compositions Toray Silicone Company Limited (JP) 1983-10-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132325-A1 THERMALLY CONDUCTIVE SILICONE COMPOSITION SMCHD1, SMC1A, SMC2 MAOA 4180/4885MAOB 3887/4885CES2 687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.